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Sulfated Polysaccharides and a Synthetic Sulfated Polymer Are Potent Inhibitors of Chlamydia trachomatis Infectivity In Vitro but Lack Protective Efficacy in an In Vivo Murine Model of Chlamydial Genital Tract Infection

Heparin, dextran sulfate, pentosan polysulfate, and a sulfated synthetic copolymer of acrylic acid and vinyl alcohol were shown to be potent inhibitors of Chlamydia trachomatis infectivity for cultured human epithelial cells. Despite their potent antichlamydial activity in vitro, neither heparin nor...

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Bibliografische gegevens
Hoofdauteurs: Su, Hua, Caldwell, Harlan D.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 1998
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC108043/
https://ncbi.nlm.nih.gov/pubmed/9488423
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