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Specific Antibody to Cryptococcus neoformans Alters Human Leukocyte Cytokine Synthesis and Promotes T-Cell Proliferation

Addition of a monoclonal antibody which binds the Cryptococcus neoformans capsule to suspensions of human monocytes, T lymphocytes, and cryptococcal cells (i) enhances interleukin-1β (IL-1β), tumor necrosis factor alpha, and IL-2 production; (ii) reduces IL-10 secretion; and (iii) promotes T-cell pr...

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Udgivet i:Infect Immun
Principais autores: Vecchiarelli, Anna, Retini, Cinzia, Monari, Claudia, Casadevall, Arturo
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1998
Fag:
Fungal and Parasitic Infections
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC108040/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9488420/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.66.3.1244-1247.1998
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