Role of Arg-Gingipain A in Virulence of Porphyromonas gingivalis

In order to access the role of the Porphyromonas gingivalis Arg-gingipain proteases in the virulence of this organism, a mutant defective in the rgpA gene was constructed in strain 381. This mutant, MT10, displayed only 40% of the Arg-specific cysteine protease activity of the wild-type strain. In a...

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Bibliographic Details
Main Authors: Tokuda, Masayuki, Karunakaran, Thonthi, Duncan, Margaret, Hamada, Nobushiro, Kuramitsu, Howard
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1998
Subjects:
Molecular and Cellular Pathogenesis
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC108029/
https://ncbi.nlm.nih.gov/pubmed/9488409
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