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Genome-wide identification of Isw2 chromatin-remodeling targets by localization of a catalytically inactive mutant

Isw2 ATP-dependent chromatin-remodeling activity is targeted to early meiotic and MATa-specific gene promoters in Saccharomyces cerevisiae. Unexpectedly, preferential cross-linking of wild-type Isw2p was not detected at these loci. Instead, the catalytically inactive Isw2p-K215R mutant is enriched a...

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Detalhes bibliográficos
Main Authors: Gelbart, Marnie E., Bachman, Nurjana, Delrow, Jeffrey, Boeke, Jef D., Tsukiyama, Toshio
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1080133/
https://ncbi.nlm.nih.gov/pubmed/15833917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1298905
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