Transposon-Derived Brucella abortus Rough Mutants Are Attenuated and Exhibit Reduced Intracellular Survival

The O antigen of Brucella abortus has been described as a major virulence determinant based on the attenuated survival of fortuitously isolated rough variants. However, the lack of genetic definition of these mutants and the virulence of naturally occurring rough species, Brucella ovis and Brucella...

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Pubblicato in:	Infect Immun
Autori principali:	Allen, Chris A., Adams, L. Garry, Ficht, Thomas A.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1998
Soggetti:	Bacterial Infections
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC108009/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9488389/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.66.3.1008-1016.1998
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