Differential modulation of microglia superoxide anion and thromboxane B(2 )generation by the marine manzamines

BACKGROUND: Thromboxane B(2 )(TXB(2)) and superoxide anion (O(2)(-)) are neuroinflammatory mediators that appear to be involved in the pathogenesis of several neurodegenerative diseases. Because activated-microglia are the main source of TXB(2 )and O(2)(- )in these disorders, modulation of their syn...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Mayer, Alejandro MS, Hall, Mary L, Lynch, Sean M, Gunasekera, Sarath P, Sennett, Susan H, Pomponi, Shirley A
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2005
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1079881/
https://ncbi.nlm.nih.gov/pubmed/15762999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2210-5-6
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