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A polymorphism at codon 31 of gene p21 is not associated with primary open angle glaucoma in Caucasians

BACKGROUND: Primary open angle glaucoma (POAG) is considered to be a neurodegenerative optic neuropathy, in which cell death occurs by apoptosis. p21, is an important protective component of the apoptotic pathway, regulating cellular arrest in the presence of DNA damage. An unstable or altered p21 p...

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Detalhes bibliográficos
Main Authors: Ressiniotis, Thomas, Griffiths, Philip G, Keers, Sharon M, Chinnery, Patrick F, Birch, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1079871/
https://ncbi.nlm.nih.gov/pubmed/15807891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2415-5-5
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