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Polymorphism screening and haplotype analysis of the tryptophan hydroxylase gene (TPH1) and association with bipolar affective disorder in Taiwan

BACKGROUND: Disturbances in serotonin neurotransmission are implicated in the etiology of many psychiatric disorders, including bipolar affective disorder (BPD). The tryptophan hydroxylase gene (TPH), which codes for the enzyme catalyzing the rate-limiting step in serotonin biosynthetic pathway, is...

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Detalhes bibliográficos
Main Authors: Lai, Te-Jen, Wu, Chia-Yen, Tsai, Hsu-Wen, Lin, Yi-Mei J, Sun, H Sunny
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1079843/
https://ncbi.nlm.nih.gov/pubmed/15799788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-6-14
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