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Transcription of the human and rodent SPAM1 / PH-20 genes initiates within an ancient endogenous retrovirus

BACKGROUND: Sperm adhesion molecule 1 (SPAM1) is the major mammalian testicular hyaluronidase and is expressed at high levels in sperm cells. SPAM1 protein is important for penetration of the cumulus cell layer surrounding the ovum, and is also involved in zona pellucida binding and sperm intracellu...

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Autores principales: Dunn, Catherine A, Mager, Dixie L
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2005
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1079825/
https://ncbi.nlm.nih.gov/pubmed/15804358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-6-47
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