Investigation of the Roles of Toxin-Coregulated Pili and Mannose-Sensitive Hemagglutinin Pili in the Pathogenesis of Vibrio cholerae O139 Infection

In this study, adult volunteers were fed tcpA and mshA deletion mutants of V. cholerae O139 strain CVD 112 to determine the role of toxin-coregulated pili (TCP) and mannose-sensitive hemagglutinin (MSHA) in intestinal colonization. Eight of 10 volunteers who received CVD 112 or CVD 112 ΔmshA shed th...

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Autori principali: Tacket, Carol O., Taylor, Ronald K., Losonsky, Genevieve, Lim, Yu, Nataro, James P., Kaper, James B., Levine, Myron M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 1998
Soggetti:
Bacterial Infections
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC107958/
https://ncbi.nlm.nih.gov/pubmed/9453628
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