A Murine Model in Which Protection Correlates with Pertussis Vaccine Efficacy in Children Reveals Complementary Roles for Humoral and Cell-Mediated Immunity in Protection against Bordetella pertussis

The results of phase 3 efficacy trials have shown that acellular and whole-cell pertussis vaccines can confer protection against whooping cough. However, despite the advances in vaccine development, clinical trials have not provided significant new information on the mechanism of protective immunity...

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Bibliographic Details
Main Authors: Mills, Kingston H. G., Ryan, Mark, Ryan, Elizabeth, Mahon, Bernard P.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1998
Subjects:
Microbial Immunity and Vaccines
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC107945/
https://ncbi.nlm.nih.gov/pubmed/9453614
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