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Mucosal Immunogenicity of a Holotoxin-Like Molecule Containing the Serine-Rich Entamoeba histolytica Protein (SREHP) Fused to the A(2) Domain of Cholera Toxin

One strategy for the induction of mucosal immune responses by oral immunization is to administer the antigen in conjunction with cholera toxin. Cholera toxin consists of one A polypeptide (CTA) which is noncovalently linked to five B subunits (CTB) via the A(2) portion of the A subunit (CTA(2)). Cou...

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Autors principals: Sultan, Faisal, Jin, Ling-ling, Jobling, Michael G., Holmes, Randall K., Stanley, Samuel L.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 1998
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC107928/
https://ncbi.nlm.nih.gov/pubmed/9453596
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