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Interleukin-4-Dependent Immunoglobulin G1 Isotype Switch in the Presence of a Polarized Antigen-Specific Th1-Cell Response to the Trypanosome Variant Surface Glycoprotein

This study examines B-cell immunoglobulin (Ig) class-switching events in the context of parasite antigen-specific Th-cell responses in experimental African trypanosomiasis. Inbred mice were infected with Trypanosoma brucei rhodesiense, and the coordinate stimulation of Th-cell cytokine responses and...

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Détails bibliographiques
Publié dans:Infect Immun
Auteurs principaux: Schopf, Lisa R., Filutowicz, Hanna, Bi, Xiao-Juan, Mansfield, John M.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 1998
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC107927/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9453595/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.66.2.451-461.1998
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