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Immunization of Aotus Monkeys with Recombinant Plasmodium falciparum Hybrid Proteins Does Not Reproducibly Result in Protection from Malaria Infection

Plasmodium falciparum antigens SERP, HRPII, MSAI, and 41-3 have shown promise as vaccine components. This study aimed at reproducing and extending previous results using three hybrid molecules. Antibody responses were reproduced in Aotus monkeys, but solid protection from a P. falciparum blood-stage...

Ausführliche Beschreibung

Gespeichert in:
Bibliografische Detailangaben
Veröffentlicht in:Infect Immun
Hauptverfasser: Kocken, Clemens H. M., Hundt, Erika, Knapp, Bernhard, Brazel, Dieter, Enders, Burkhard, Narum, David L., Wubben, Jaqueline A. M., Thomas, Alan W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 1998
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC107908/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9423884/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.66.1.373-375.1998
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