Microbial Pathogenesis in Cystic Fibrosis: Pulmonary Clearance of Mucoid Pseudomonas aeruginosa and Inflammation in a Mouse Model of Repeated Respiratory Challenge

Chronic endobronchiolitis compounded by recurring Pseudomonas aeruginosa infections is the major cause of morbidity and mortality in patients with cystic fibrosis (CF). In this study, a mouse model of repeated respiratory exposure to P. aeruginosa was established to facilitate investigations of fact...

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Publié dans:	Infect Immun
Auteurs principaux:	Yu, H., Hanes, M., Chrisp, C. E., Boucher, J. C., Deretic, V.
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 1998
Sujets:	Host Response and Inflammation
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC107888/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9423869/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.66.1.280-288.1998
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