Functional Similarities between the Listeria monocytogenes Virulence Regulator PrfA and Cyclic AMP Receptor Protein: the PrfA* (Gly145Ser) Mutation Increases Binding Affinity for Target DNA

Most Listeria monocytogenes virulence genes are positively regulated by the PrfA protein, a transcription factor sharing sequence similarities with cyclic AMP (cAMP) receptor protein (CRP). Its coding gene, prfA, is regulated by PrfA itself via an autoregulatory loop mediated by the upstream PrfA-de...

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Detalhes bibliográficos
Main Authors: Vega, Yolanda, Dickneite, Carmen, Ripio, María-Teresa, Böckmann, Regine, González-Zorn, Bruno, Novella, Susana, Domínguez-Bernal, Gustavo, Goebel, Werner, Vázquez-Boland, José A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1998
Assuntos:
Genetics and Molecular Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC107770/
https://ncbi.nlm.nih.gov/pubmed/9852011
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