A Combination of Three Mutations, dcd, pyrH, and cdd, Establishes Thymidine (Deoxyuridine) Auxotrophy in thyA(+) Strains of Salmonella typhimurium

The dum gene of Salmonella typhimurium was originally identified as a gene involved in dUMP synthesis (C. F. Beck et al., J. Bacteriol. 129:305–316, 1977). In the genetic background used in their selection, the joint acquisition of a dcd (dCTP deaminase) and a dum mutation established a condition of...

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Vydáno v:	J Bacteriol
Hlavní autoři:	Krogan, Nevan J., Zaharik, Michelle L., Neuhard, Jan, Kelln, Rod A.
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 1998
Témata:	Physiology and Metabolism
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC107662/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9811646/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.180.22.5891-5895.1998
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