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Interaction of RecBCD Enzyme with DNA at Double-Strand Breaks Produced in UV-Irradiated Escherichia coli: Requirement for DNA End Processing

The RecBCD enzyme has a powerful duplex DNA exonuclease activity in vivo. We found that this activity decreased strongly when cells were irradiated with UV light (135 J/m(2)). The activity decrease was seen by an increase in survival of phage T4 2(−) of about 200-fold (phage T4 2(−) has defective du...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:J Bacteriol
Hauptverfasser: Thoms, Brigitte, Wackernagel, Wilfried
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 1998
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC107622/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9791113/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.180.21.5639-5645.1998
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