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Identification of an N-Terminal Region of Sigma 54 Required for Enhancer Responsiveness

Sigma 54 associates with bacterial core RNA polymerase and converts it into an enhancer-responsive enzyme. Deletion of the N-terminal 40 amino acids is known to result in loss of the ability to respond to enhancer binding proteins. In this work PCR mutagenesis and genetic screens were used to identi...

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Detalhes bibliográficos
Main Authors: Syed, Adeela, Gralla, Jay D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC107619/
https://ncbi.nlm.nih.gov/pubmed/9791110
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