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Autoregulation of the pTF-FC2 Proteic Poison-Antidote Plasmid Addiction System (pas) Is Essential for Plasmid Stabilization

The pasABC genes of the proteic plasmid addiction system of broad-host-range plasmid pTF-FC2 were autoregulated. The PasA antidote was able to repress the operon 25-fold on its own, and repression was increased to 100-fold when the PasB toxin was also present. Autoregulation appears to be an essenti...

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Autores principales: Smith, Anthony S. G., Rawlings, Douglas E.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 1998
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC107599/
https://ncbi.nlm.nih.gov/pubmed/9765582
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