Analogs of the Autoinducer 3-Oxooctanoyl-Homoserine Lactone Strongly Inhibit Activity of the TraR Protein of Agrobacterium tumefaciens

The TraR and TraI proteins of Agrobacterium tumefaciens mediate cell-density-dependent expression of the Ti plasmid tra regulon. TraI synthesizes the autoinducer pheromone N-(3-oxooctanoyl)-l-homoserine lactone (3-oxo-C(8)-HSL), while TraR is an 3-oxo-C(8)-HSL-responsive transcriptional activator. W...

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Main Authors: Zhu, Jun, Beaber, John W., Moré, Margret I., Fuqua, Clay, Eberhard, Anatol, Winans, Stephen C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1998
Assuntos:
Physiology and Metabolism
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC107588/
https://ncbi.nlm.nih.gov/pubmed/9765571
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