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Increased Multinucleoside Drug Resistance and Decreased Replicative Capacity of a Human Immunodeficiency Virus Type 1 Variant with an 8-Amino-Acid Insert in the Reverse Transcriptase

Resistance to antiretroviral drugs is generally conferred by specific amino acid substitutions, rather than insertions or deletions, in reverse transcriptase (RT) of human immunodeficiency virus type 1 (HIV-1). The exception to these findings is the amino acid insertions found in the β3-β4 loop of t...

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Bibliografski detalji
Glavni autori: van der Hoek, Lia, Back, Nicole, Jebbink, Maarten F., de Ronde, Anthony, Bakker, Margreet, Jurriaans, Suzanne, Reiss, Peter, Parkin, Neil, Berkhout, Ben
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2005
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1075723/
https://ncbi.nlm.nih.gov/pubmed/15731248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.6.3536-3543.2005
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