Human Cytomegalovirus Immediate-Early 2 Gene Expression Blocks Virus-Induced Beta Interferon Production

The effect of human cytomegalovirus (HCMV) gene expression on beta interferon (IFN-β) expression was examined. We demonstrate that the HCMV immediate-early 2 (IE2) gene product IE86 can effectively block the induction of IFN-β during HCMV infection. IE86 also efficiently blocked the induction of IFN...

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Bibliographic Details
Main Authors: Taylor, R. Travis, Bresnahan, Wade A.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2005
Subjects:
Virus-Cell Interactions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1075717/
https://ncbi.nlm.nih.gov/pubmed/15731283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.6.3873-3877.2005
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