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Overproduction of a Functional Fatty Acid Biosynthetic Enzyme Blocks Fatty Acid Synthesis in Escherichia coli

β-Ketoacyl-acyl carrier protein (ACP) synthetase II (KAS II) is one of three Escherichia coli isozymes that catalyze the elongation of growing fatty acid chains by condensation of acyl-ACP with malonyl-ACP. Overexpression of this enzyme has been found to be extremely toxic to E. coli, much more so t...

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Pubblicato in:J Bacteriol
Autori principali: Subrahmanyam, Satyanarayana, Cronan, John E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 1998
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC107473/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9721301/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.180.17.4596-4602.1998
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