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The G Protein-coupled Receptor Gpr1 and the Gα Protein Gpa2 Act through the cAMP-Protein Kinase A Pathway to Induce Morphogenesis in Candida albicans

We investigated the role in cell morphogenesis and pathogenicity of the Candida albicans GPR1 gene, encoding the G protein-coupled receptor Gpr1. Deletion of C. albicans GPR1 has only minor effects in liquid hypha-inducing media but results in strong defects in the yeast-to-hypha transition on solid...

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Detalhes bibliográficos
Main Authors: Maidan, Mykola M., De Rop, Larissa, Serneels, Joke, Exler, Simone, Rupp, Steffen, Tournu, Hélène, Thevelein, Johan M., Van Dijck, Patrick
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1073676/
https://ncbi.nlm.nih.gov/pubmed/15673611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E04-09-0780
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