The Functionally Conserved Nucleoporins Nup124p from Fission Yeast and the Human Nup153 Mediate Nuclear Import and Activity of the Tf1 Retrotransposon and HIV-1 Vpr

We report that the fission yeast nucleoporin Nup124p is required for the nuclear import of both, retrotransposon Tf1-Gag as well as the retroviral HIV-1 Vpr. Failure to import Tf1-Gag into the nucleus in a nup124 null mutant resulted in complete loss of Tf1 transposition. Similarly, nuclear import o...

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Main Authors: Varadarajan, Padmapriya, Mahalingam, Sundarasamy, Liu, Peiyun, Ng, Sarah Boon Hsi, Gandotra, Sheetal, Dorairajoo, Desmond Suresh Kumar, Balasundaram, David
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2005
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1073664/
https://ncbi.nlm.nih.gov/pubmed/15659641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E04-07-0583
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