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Disruption of the Candida albicans TPS1 Gene Encoding Trehalose-6-Phosphate Synthase Impairs Formation of Hyphae and Decreases Infectivity

The TPS1 gene from Candida albicans, which encodes trehalose-6-phosphate synthase, has been cloned by functional complementation of a tps1 mutant from Saccharomyces cerevisiae. In contrast with the wild-type strain, the double tps1/tps1 disruptant did not accumulate trehalose at stationary phase or...

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Detalhes bibliográficos
Publicado no:J Bacteriol
Principais autores: Zaragoza, Oscar, Blazquez, Miguel A., Gancedo, Carlos
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC107363/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9683476/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.180.15.3809-3815.1998
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