Debrisoquine hydroxylase gene polymorphism in familial Parkinson's disease.

Recent molecular genetic studies of the cytochrome P-450 system enzyme CYP2D6, which hydroxylates debrisoquine, have indicated an excess of mutant alleles in patients with Parkinson's disease compared with controls. This indicates that the CYP2D6 locus confers genetic susceptibility to Parkinso...

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Bibliografske podrobnosti
Main Authors: Planté-Bordeneuve, V, Davis, M B, Maraganore, D M, Marsden, C D, Harding, A E
Format: Artigo
Jezik:Inglês
Izdano: 1994
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1073072/
https://ncbi.nlm.nih.gov/pubmed/8057112
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