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Correcting errors in synthetic DNA through consensus shuffling
Although efficient methods exist to assemble synthetic oligonucleotides into genes and genomes, these suffer from the presence of 1–3 random errors/kb of DNA. Here, we introduce a new method termed consensus shuffling and demonstrate its use to significantly reduce random errors in synthetic DNA. In...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1072806/ https://ncbi.nlm.nih.gov/pubmed/15800206 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gni053 |
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