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The Streptomyces peucetius dpsY and dnrX Genes Govern Early and Late Steps of Daunorubicin and Doxorubicin Biosynthesis

The Streptomyces peucetius dpsY and dnrX genes govern early and late steps in the biosynthesis of the clinically valuable antitumor drugs daunorubicin (DNR) and doxorubicin (DXR). Although their deduced products resemble those of genes thought to be involved in antibiotic production in several other...

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Auteurs principaux: Lomovskaya, Natalia, Doi-Katayama, Yukiko, Filippini, Sylvia, Nastro, Cecilia, Fonstein, Leonid, Gallo, Mark, Colombo, Anna Luisa, Hutchinson, C. Richard
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 1998
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC107179/
https://ncbi.nlm.nih.gov/pubmed/9573189
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