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The Folate Branch of the Methionine Biosynthesis Pathway in Streptomyces lividans: Disruption of the 5,10-Methylenetetrahydrofolate Reductase Gene Leads to Methionine Auxotrophy

In enterobacteria, the methyl group of methionine is donated by 5-methyltetrahydrofolate that is synthesized from N(5,10)-methylenetetrahydrofolate by the 5,10-methylenetetrahydrofolate reductase. The Streptomyces lividans metF gene, which encodes 5,10-methylenetetrahydrofolate reductase, has been c...

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Détails bibliographiques
Auteurs principaux: Blanco, Jorge, Coque, Juan Jose R., Martin, Juan F.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 1998
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC107064/
https://ncbi.nlm.nih.gov/pubmed/9515933
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