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Renal cell–expressed TNF receptor 2, not receptor 1, is essential for the development of glomerulonephritis

TNF is essential for the development of glomerulonephritis, an immune-mediated disorder that is a major cause of renal failure worldwide. However, TNF has proinflammatory and immunosuppressive properties that may segregate at the level of the 2 TNF receptors (TNFRs), TNFR1 and TNFR2. TNFR1-deficient...

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Detalhes bibliográficos
Main Authors: Vielhauer, Volker, Stavrakis, George, Mayadas, Tanya N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1070636/
https://ncbi.nlm.nih.gov/pubmed/15841213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200523348
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