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Renal cell–expressed TNF receptor 2, not receptor 1, is essential for the development of glomerulonephritis
TNF is essential for the development of glomerulonephritis, an immune-mediated disorder that is a major cause of renal failure worldwide. However, TNF has proinflammatory and immunosuppressive properties that may segregate at the level of the 2 TNF receptors (TNFRs), TNFR1 and TNFR2. TNFR1-deficient...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Clinical Investigation
2005
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1070636/ https://ncbi.nlm.nih.gov/pubmed/15841213 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200523348 |
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