Effects of the PPARγ agonist pioglitazone on lipoprotein metabolism in patients with type 2 diabetes mellitus

Elevated plasma levels of VLDL triglycerides (TGs) are characteristic of patients with type 2 diabetes mellitus (T2DM) and are associated with increased production rates (PRs) of VLDL TGs and apoB. Lipoprotein lipase–mediated (LPL-mediated) lipolysis of VLDL TGs may also be reduced in T2DM if the le...

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Main Authors: Nagashima, Kazunori, Lopez, Carlos, Donovan, Daniel, Ngai, Colleen, Fontanez, Nelson, Bensadoun, André, Fruchart-Najib, Jamila, Holleran, Steve, Cohn, Jeffrey S., Ramakrishnan, Rajasekhar, Ginsberg, Henry N.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2005
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1070635/
https://ncbi.nlm.nih.gov/pubmed/15841215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200523219
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