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Regulation of NAD Synthesis by the Trifunctional NadR Protein of Salmonella enterica

The three activities of NadR were demonstrated in purified protein and assigned to separate domains by missense mutations. The N-terminal domain represses transcription of genes for NAD synthesis and salvage. The C-terminal domain has nicotinamide ribose kinase (NmR-K; EC 2.7.1.22) activity, which i...

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Bibliografiske detaljer
Main Authors: Grose, Julianne H., Bergthorsson, Ulfar, Roth, John R.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1070365/
https://ncbi.nlm.nih.gov/pubmed/15805524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.187.8.2774-2782.2005
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