Noninvasive Visualization of the Activated αvβ3 Integrin in Cancer Patients by Positron Emission Tomography and [(18)F]Galacto-RGD

BACKGROUND: The integrin αvβ3 plays an important role in angiogenesis and tumor cell metastasis, and is currently being evaluated as a target for new therapeutic approaches. Several techniques are being studied to enable noninvasive determination of αvβ3 expression. We developed [(18)F]Galacto-RGD,...

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Main Authors: Haubner, Roland, Weber, Wolfgang A, Beer, Ambros J, Vabuliene, Eugenija, Reim, Daniel, Sarbia, Mario, Becker, Karl-Friedrich, Goebel, Michael, Hein, Rüdiger, Wester, Hans-Jürgen, Kessler, Horst, Schwaiger, Markus
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2005
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1069665/
https://ncbi.nlm.nih.gov/pubmed/15783258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.0020070
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