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Inhibition of Murine Leukemia Virus Envelope Protein (Env) Processing by Intracellular Expression of the Env N-Terminal Heptad Repeat Region

A conserved structural motif in the envelope proteins of several viruses consists of an N-terminal, alpha-helical, trimerization domain and a C-terminal region that refolds during fusion to bind the N-helix trimer. Interaction between the N and C regions is believed to pull viral and target membrane...

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Autors principals: Ou, Wu, Silver, Jonathan
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1069576/
https://ncbi.nlm.nih.gov/pubmed/15795264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.8.4782-4792.2005
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