Weak Palindromic Consensus Sequences Are a Common Feature Found at the Integration Target Sites of Many Retroviruses

Integration into the host genome is one of the hallmarks of the retroviral life cycle and is catalyzed by virus-encoded integrases. While integrase has strict sequence requirements for the viral DNA ends, target site sequences have been shown to be very diverse. We carefully examined a large number...

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Bibliografiske detaljer
Main Authors: Wu, Xiaolin, Li, Yuan, Crise, Bruce, Burgess, Shawn M., Munroe, David J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2005
Fag:
Genome Replication and Regulation of Viral Gene Expression
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1069554/
https://ncbi.nlm.nih.gov/pubmed/15795304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.8.5211-5214.2005
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