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VALUE OF ED(50) TESTING IN ASSESSING HAZARDS OF ACUTE POISONING BY CARBAMATES AND ORGANOPHOSPHATES

It is shown from the kinetics of inhibition of cholinesterase by N-methylcarbamates and organophosphates that the LD(50) dose is likely to be a much greater multiple of the dose causing signs of poisoning in 50% of the animals (the ED(50)) for the carbamates than for the organophosphates. The expect...

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Autors principals: Vandekar, M., Reiner, E., Svetličić, B., Fajdetić, T.
Format: Artigo
Idioma:Inglês
Publicat: 1965
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1069386/
https://ncbi.nlm.nih.gov/pubmed/5836574
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