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Mutational Analysis of UMP Kinase from Escherichia coli

UMP kinase from Escherichia coli is one of the four regulatory enzymes involved in the de novo biosynthetic pathway of pyrimidine nucleotides. This homohexamer, with no counterpart in eukarya, might serve as a target for new antibacterial drugs. Although the bacterial enzyme does not show sequence s...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:J Bacteriol
Hauptverfasser: Bucurenci, Nadia, Serina, Lidia, Zaharia, Cristina, Landais, Stéphanie, Danchin, Antoine, Bârzu, Octavian
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 1998
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC106910/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9457846/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.180.3.473-477.1998
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