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Biochemical and Genetic Characterization of an FK506-Sensitive Peptidyl Prolyl cis-trans Isomerase from a Thermophilic Archaeon, Methanococcus thermolithotrophicus

A peptidyl prolyl cis-trans isomerase (PPIase) was purified from a thermophilic methanogen, Methanococcus thermolithotrophicus. The PPIase activity was inhibited by FK506 but not by cyclosporine. The molecular mass of the purified enzyme was estimated to be 16 kDa by sodium dodecyl sulfate-polyacryl...

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Bibliografiska uppgifter
Huvudupphovsmän: Furutani, Masahiro, Iida, Toshii, Yamano, Shigeyuki, Kamino, Kei, Maruyama, Tadashi
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 1998
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC106894/
https://ncbi.nlm.nih.gov/pubmed/9440528
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