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Identification and Characterization of aarF, a Locus Required for Production of Ubiquinone in Providencia stuartii and Escherichia coli and for Expression of 2′-N-Acetyltransferase in P. stuartii

Providencia stuartii contains a chromosomal 2′-N-acetyltransferase [AAC(2′)-Ia] involved in the O acetylation of peptidoglycan. The AAC(2′)-Ia enzyme is also capable of acetylating and inactivating certain aminoglycosides and confers high-level resistance to these antibiotics when overexpressed. We...

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Détails bibliographiques
Publié dans:J Bacteriol
Auteurs principaux: Macinga, David R., Cook, Gregory M., Poole, Robert K., Rather, Philip N.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 1998
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC106858/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9422602/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.180.1.128-135.1998
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