Autoantibodies specific for apoptotic U1-70K are superior serological markers for mixed connective tissue disease

Modifications occurring on autoantigens during cell death have been proposed to have a role in the initiation of autoimmune diseases. Patients suffering from mixed connective tissue disease (MCTD) produce autoantibodies directed to U1 small nuclear ribonucleoprotein (snRNP), and antibodies against a...

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Bibliographic Details
Main Authors: Hof, Daniëlle, Cheung, Kalok, de Rooij, Dirk-Jan RAM, van den Hoogen, Frank H, Pruijn, Ger JM, van Venrooij, Walther J, Raats, Jos MH
Format: Artigo
Language:Inglês
Published: BioMed Central 2005
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1065328/
https://ncbi.nlm.nih.gov/pubmed/15743477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar1490
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