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Inhibition of antithrombin by hyaluronic acid may be involved in the pathogenesis of rheumatoid arthritis

Thrombin is a key factor in the stimulation of fibrin deposition, angiogenesis, proinflammatory processes, and proliferation of fibroblast-like cells. Abnormalities in these processes are primary features of rheumatoid arthritis (RA) in synovial tissues. Tissue destruction in joints causes the accum...

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Detalhes bibliográficos
Main Authors: Chang, Xiaotian, Yamada, Ryo, Yamamoto, Kazuhiko
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1065325/
https://ncbi.nlm.nih.gov/pubmed/15743473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar1487
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