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Stimulation of Fas agonistic antibody–mediated apoptosis by heparin-like agents suppresses Hsp27 but not Bcl-2 protective activity

We report that in Jurkat T cells or freshly isolated T lymphocytes, physiological concentrations of high– molecular weight sulfated polysaccharides such as heparin, heparan sulfate, and dextran sulfate significantly increased the percentage of cell death induced by Fas IgM agonistic antibody. The ph...

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Detalhes bibliográficos
Main Authors: Manero, Florence, Ljubic-Thibal, Vesna, Moulin, Maryline, Goutagny, Nadège, Yvin, Jean-Claude, Arrigo, André-Patrick
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Stress Society International 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1065295/
https://ncbi.nlm.nih.gov/pubmed/15497502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1379/CSC-16R.1
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