Characterization of the Acetate Binding Pocket in the Methanosarcina thermophila Acetate Kinase

Acetate kinase catalyzes the reversible magnesium-dependent synthesis of acetyl phosphate by transfer of the ATP γ-phosphoryl group to acetate. Inspection of the crystal structure of the Methanosarcina thermophila enzyme containing only ADP revealed a solvent-accessible hydrophobic pocket formed by...

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Bibliografiske detaljer
Main Authors: Ingram-Smith, Cheryl, Gorrell, Andrea, Lawrence, Sarah H., Iyer, Prabha, Smith, Kerry, Ferry, James G.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2005
Fag:
Enzymes and Proteins
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1065240/
https://ncbi.nlm.nih.gov/pubmed/15774882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.187.7.2386-2394.2005
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