N Glycolylation of the Nucleotide Precursors of Peptidoglycan Biosynthesis of Mycobacterium spp. Is Altered by Drug Treatment

The peptidoglycan of Mycobacterium spp. reportedly has some unique features, including the occurrence of N-glycolylmuramic rather than N-acetylmuramic acid. However, very little is known of the actual biosynthesis of mycobacterial peptidoglycan, including the extent and origin of N glycolylation. In...

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Bibliographic Details
Main Authors: Mahapatra, Sebabrata, Scherman, Hataichanok, Brennan, Patrick J., Crick, Dean C.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2005
Subjects:
Physiology and Metabolism
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1065221/
https://ncbi.nlm.nih.gov/pubmed/15774877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.187.7.2341-2347.2005
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