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Cholesterol targeting alters lipid raft composition and cell survival in prostate cancer cells and xenografts
Lipid rafts are cholesterol- and sphingolipid-enriched microdomains in cell membranes that regulate phosphorylation cascades originating from membrane-bound proteins. In this study, we tested whether alteration of the cholesterol content of lipid rafts in prostate cancer (PCa) cell membranes affects...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1064980/ https://ncbi.nlm.nih.gov/pubmed/15776112 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200519935 |
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