Distinct Roles of Pattern Recognition Receptors CD14 and Toll-Like Receptor 4 in Acute Lung Injury

Acute lung injury (ALI) induced by lipopolysaccharide (LPS) is a major cause of mortality among humans. ALI is characterized by microvascular protein leakage, neutrophil influx, and expression of proinflammatory mediators, followed by severe lung damage. LPS binding to its receptors is the crucial s...

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Detalhes bibliográficos
Main Authors: Jeyaseelan, Samithamby, Chu, Hong Wei, Young, Scott K., Freeman, Mason W., Worthen, G. Scott
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Host Response and Inflammation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1064978/
https://ncbi.nlm.nih.gov/pubmed/15731076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.3.1754-1763.2005
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