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Distinct Roles of Pattern Recognition Receptors CD14 and Toll-Like Receptor 4 in Acute Lung Injury

Acute lung injury (ALI) induced by lipopolysaccharide (LPS) is a major cause of mortality among humans. ALI is characterized by microvascular protein leakage, neutrophil influx, and expression of proinflammatory mediators, followed by severe lung damage. LPS binding to its receptors is the crucial s...

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Autors principals: Jeyaseelan, Samithamby, Chu, Hong Wei, Young, Scott K., Freeman, Mason W., Worthen, G. Scott
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1064978/
https://ncbi.nlm.nih.gov/pubmed/15731076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.3.1754-1763.2005
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