Susceptibility of Germfree Phagocyte Oxidase- and Nitric Oxide Synthase 2-Deficient Mice, Defective in the Production of Reactive Metabolites of Both Oxygen and Nitrogen, to Mucosal and Systemic Candidiasis of Endogenous Origin

Mice deficient for phagocyte oxidase (Phox) and nitric oxide synthase 2 (NOS2) (gp91(phox−/−)/NOS2(−/−)), defective in the production of both reactive oxygen intermediates (ROI) and reactive nitrogen intermediates (RNI), were used to investigate the role of phagocytic cells during mucosal and system...

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Detalhes bibliográficos
Main Authors: Balish, Edward, Warner, Thomas F., Nicholas, Peter J., Paulling, Emily E., Westwater, Caroline, Schofield, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Fungal and Parasitic Infections
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1064974/
https://ncbi.nlm.nih.gov/pubmed/15731028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.3.1313-1320.2005
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