The Gamma Interferon Receptor Is Required for the Protective Pulmonary Inflammatory Response to Cryptococcus neoformans

Mice with a null deletion mutation in the gamma interferon (IFN-γ) receptor gene were used to study the role of IFN-γ responsiveness during experimental pulmonary cryptococcosis. Cryptococcus neoformans was inoculated intratracheally into mice lacking the IFN-γ receptor gene (IFN-γR(−/−)) and into c...

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Main Authors: Chen, Gwo-Hsiao, McDonald, Roderick A., Wells, Jason C., Huffnagle, Gary B., Lukacs, Nicholas W., Toews, Galen B.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2005
Assuntos:
Fungal and Parasitic Infections
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1064966/
https://ncbi.nlm.nih.gov/pubmed/15731080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.3.1788-1796.2005
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